Inflammatory white blood cells in semen is related to semen quality affecting fertility. The role of inflammatory cells on the seminal levels of various cytokines associated with inflammation and sperm motility is evaluated. Semens from 10
healthy
males
and 20 chronic prostatitis patients were evaluated for the levels of interleukin(IL)-1α, IL-6, IL-8 and tumor necrosis factor(TNF)-α. Motility parameters were recorded using dhamilton-Thorne computer semen analysis system. Sperm motiity
parameters
such as including average path velocity9VAP0, straignt line velocity9VSL), curdvilinear velocity(LIN), elongation and area in control and chronic prostatitis patients were 44.9±2.4/30.5±1.1(μm/sec0, 64.2±3.9/58.0±2.4(μm/sec0,
3.3±0.24/4.8±0.3(μm), 19.8±3.7/13.9±0.3(Hz), 77.7±5.1/78.8±1.2(%),50.6±17.5/53.5±1.9(%), 66.8±5.4/57.8±1.1(%), 2.9±0.3/3.8±0.1(μmsq), respectively. Statistical significnace was noted in VAP, VSL, ALH, BCF, elongation and area. Semen
levels
of IL-1α, IL-6, IL-8 and TNF-α in control and chronic prostiatitis patients are 15.1±1.5/52.9±14.2(pg/ml), 10.5±2.2/28.3±12.2(pg/ml), 1.60±0.38/0.62±0.26(μg/L), 11.8±2.5/21.7±4.0(pg/ml) stastistically significant inall. For combined
parameters, the correlation coefficient of IL-1α and VSL, ALH, Area were 0.40, 0.41, 0.37 respectively which were significant. The correlation coefficient of IL-8 and VAP, VSL, VCL, ALH, BCF, Elongation Afrea were 0.48, 0.49, 0.39, 0.41, 0.59,
0.66
respectively which were also significant. Semianl inflammatory cytokines are present in increased quantities if inflammatory white blood cells are present in semen and this increase rnight be to sperm motility.
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